Which finding indicates a therapeutic effect of mannitol in a patient with increased intracranial pressure?

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Multiple Choice

Which finding indicates a therapeutic effect of mannitol in a patient with increased intracranial pressure?

Explanation:
Mannitol lowers intracranial pressure by drawing water out of swollen brain tissue into the bloodstream, which happens when plasma osmolality rises. A serum osmolarity of about 310 mOsm/L shows the osmotic gradient is established and the drug is producing the intended effect. Decreased ICP on imaging would be a result of this process, but the direct indicator of the therapeutic action is the increased serum osmolality. The other options do not directly reflect the osmotic mechanism or its immediate effect.

Mannitol lowers intracranial pressure by drawing water out of swollen brain tissue into the bloodstream, which happens when plasma osmolality rises. A serum osmolarity of about 310 mOsm/L shows the osmotic gradient is established and the drug is producing the intended effect. Decreased ICP on imaging would be a result of this process, but the direct indicator of the therapeutic action is the increased serum osmolality. The other options do not directly reflect the osmotic mechanism or its immediate effect.

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